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Barbara Mania-Farnell, Ph.D.

Office: Gyte 288
Telephone: (219) 989-2014


M.S. Social Sciences, University of Chicago, Chicago, Il
Ph.D. Neurobiology and Physiology, Northwestern University, Evanston, Il

Research Interests

     I am currently working in collaboration with Dr.Chandra S. Mayanil (Director of Neural Tube Research) at Children’s Memorial Hospital, affiliated with Northwestern University Feinberg School of Medicine. The project I am working on focuses on the role of the transcription factors in neural tube development and neural crest cell differentiation.

Memberships in Societies

Society for Neuroscience
Sigma Xi, The Scientific Research Society
Project Kaleidoscope (PKAL): Faculty for the 21st Century
American Association for the Advancement of Science

Selected Publications:

(abstracts are linked to authors name, please click to view)

Regulation of murine TGFbeta2 by Pax3 during early embryonic development.
J Biol Chem. 2006 Aug 25;281(34):24544-52. Epub 2006 Jun 19.
PMID: 16787918 [PubMed - indexed for MEDLINE]


Interaction of the extracellular domain of the epidermal growth factor receptor with gangliosides.
J Biol Chem. 2002 Mar 22;277(12):10108-13. Epub 2002 Jan 16.
PMID: 11796728 [PubMed - indexed for MEDLINE]


Microarray analysis detects novel Pax3 downstream target genes.
J Biol Chem. 2001 Dec 28;276(52):49299-309. Epub 2001 Oct 5.
PMID: 11590174 [PubMed - indexed for MEDLINE]


Overexpression of murine Pax3 increases NCAM polysialylation in a human medulloblastoma cell line.
J Biol Chem. 2000 Jul 28;275(30):23259-66.
PMID: 10770948 [PubMed - indexed for MEDLINE]


Modulation of EGF receptor activity by changes in the GM3 content in a human epidermoid carcinoma cell line, A431.
Exp Cell Res. 2000 Apr 10;256(1):74-82.
PMID: 10739654 [PubMed - indexed for MEDLINE]


Metformin modulates insulin receptor signaling in normal and cholesterol-treated human hepatoma cells (HepG2).
Eur J Pharmacol. 1999 Jul 21;377(2-3):241-52.
PMID: 10456437 [PubMed - indexed for MEDLINE]



Sci 114 - Introduction to Life Sciences

Biol 125 - Human Biology

Biol 213 - Anatomy and Physiology

Biol 525 - Principles of Neurobiology

Biol 566 - Developmental Biology

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